transmutes takes a lot of time...you can only transmute once a day.
The rate for procs are low (it took me 12 days to get my first x2 primal might). However, if you are lucky, you can get a x4 or x5 and cash it in.
You will need to proc a x2 4 times to get your initial investment back and that can take weeks (assuming you are diligent and transmute once daily).
Once you get your investment back, then all the rest are profit.