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#27 Sep 18 2008 at 7:47 AM Rating: Good
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yossarian wrote:
Aripyanfar wrote:
Youssarian, try searching for "endocrine disrupter/s" instead, then.


Okay. "An endocrine disrupter is defined as “an exogenous substance that causes adverse health effects in an intact organism, or its progeny, consequent to changes in endocrine function” [8]. EDCs constitute, therefore, a class of substances which is not defined by chemical nature but by biological effect [9]. Thus, a wide variety of pollutants which have been reported to disrupt normal pathways in animals, including pesticides [10], polycyclic aromatic hydrocarbons [11], phthalate plasticizers [12], certain polychlorinated biphenyls, dioxins, furans, alkylphenols, synthetic steroids, and natural products such as phytoestrogens, are collectively referred to as EDCs [1, 13 and 14]."

This is from an article by: Maria J. López de Alda and Damià Barceló in Journal of Chromatography A, an article I picked at semi-random.

This is not just plastics, but a broad variety of chemicals. Will follow up later when I have more time.

*nod nod*

That's the stuff. Or class of stuff, perhaps? In biological science endocrine disrupters are also known as xenohormones, (foreign hormones) particularly because they are chemicals that come from the outside environment into a human or animal body, and act on the hormone system, instead of being generated inside the human or animal body.

There are a lot of plants that are xenohormones too, but in general the plants that we eat that are xenohormones aren't as problematic. That is, we've been eating some xenohormonal plants for a very long time, and have had a stable pattern of pathology. In the last 60 years or so, there's been an enormous upswing of xenohormones released into the environment and used as consumer products from synthetic chemical/crude oil sources, which has coincided with a huge upswing in some pathologies. The correlation has made a lot of biological scientists very nervous, and there's been a lot of studies investigating causative links. So lobbyists are focusing on asking regulators to investigate and regulate xenohoromones/endocrine disrupters of synthetic/crude oil origin.
#28 Sep 18 2008 at 8:04 AM Rating: Default
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.
#29 Sep 18 2008 at 8:04 AM Rating: Decent
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Samira wrote:
Uglysasquatch, Mercenary Major wrote:
Something tells me that I'm likely to feed them worse things as they grow up, such as McD's (or any fast food), children's marketed food, etc...


I might pay a little more attention to this once it gets past "linked to" status.



A guild mate of mine in EQ used to put macaroni and cheese into a McDonald's box to fool his four-year-old into eating it.



That kid is messed up. Everyone loves macaroni and cheese.
#30 Sep 18 2008 at 8:04 AM Rating: Decent
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DaimenKain wrote:
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.


You're an idiot.
#31 Sep 18 2008 at 8:05 AM Rating: Good
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MentalFrog wrote:
DaimenKain wrote:
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.


You're an idiot.
How often do you need to see this before you start believing me Damien?
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#32 Sep 18 2008 at 8:12 AM Rating: Default
MentalFrog wrote:
DaimenKain wrote:
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.


You're an idiot.


Please MentalFrog, let me know the error of my ways.

If you're gonna worry about what the plastic baby bottle is doing to your kid, then you should keep them locked in their room, since there are plenty of more dangerous things out there than plastic.
#33 Sep 18 2008 at 8:19 AM Rating: Good
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DaimenKain wrote:
MentalFrog wrote:
DaimenKain wrote:
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.


You're an idiot.


Please MentalFrog, let me know the error of my ways.

If you're gonna worry about what the plastic baby bottle is doing to your kid, then you should keep them locked in their room, since there are plenty of more dangerous things out there than plastic.



I let you know you're an idiot. What's more to explain?
#34 Sep 18 2008 at 8:20 AM Rating: Default
MentalFrog wrote:
DaimenKain wrote:
MentalFrog wrote:
DaimenKain wrote:
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.


You're an idiot.


Please MentalFrog, let me know the error of my ways.

If you're gonna worry about what the plastic baby bottle is doing to your kid, then you should keep them locked in their room, since there are plenty of more dangerous things out there than plastic.



I let you know you're an idiot. What's more to explain?


Ok...no actual response, just an insult...gotcha.

And I'M the idiot. lol
#35 Sep 18 2008 at 8:21 AM Rating: Decent
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DaimenKain wrote:
MentalFrog wrote:
DaimenKain wrote:
MentalFrog wrote:
DaimenKain wrote:
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.


You're an idiot.


Please MentalFrog, let me know the error of my ways.

If you're gonna worry about what the plastic baby bottle is doing to your kid, then you should keep them locked in their room, since there are plenty of more dangerous things out there than plastic.



I let you know you're an idiot. What's more to explain?


Ok...no actual response, just an insult...gotcha.

And I'M the idiot. lol


Ever tried explaining physics to a two year old? It's a waste of time.
#36 Sep 18 2008 at 8:24 AM Rating: Good
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DaimenKain wrote:
MentalFrog wrote:
DaimenKain wrote:
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.


You're an idiot.


Please MentalFrog, let me know the error of my ways.

If you're gonna worry about what the plastic baby bottle is doing to your kid, then you should keep them locked in their room, since there are plenty of more dangerous things out there than plastic.

They used to make some children's toys out of Asbestos. They used to say smoking didn't cause lung cancer.

It's not all plastics. But it's many palstics.

I can just see a senate enquiry in 30 years time:

"Now, Mr Smith, tell me exactly when you were first aware that the plastic tub your margarine is sold in was made from an endocrine disrupting plastic?"

Edited, Sep 18th 2008 12:20pm by Aripyanfar
#37 Sep 18 2008 at 8:25 AM Rating: Decent
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DaimenKain wrote:
MentalFrog wrote:
DaimenKain wrote:
Oh well, who cares. The same people who are worried about plastic baby bottles are the same people who will drive with their kids in a car, or take them outside which is much more dangerous.


You're an idiot.


Please MentalFrog, let me know the error of my ways.

If you're gonna worry about what the plastic baby bottle is doing to your kid, then you should keep them locked in their room, since there are plenty of more dangerous things out there than plastic.

It's a stupid comparison. Your comparing totally different things. Is it more risky to "DRIVE" your kid to the hospital when they're having trouble breathing or leave them in their safe room and off the streets?

Yes, there are more dangerous things than plastic to an individual growing up. In fact, you have to weigh the risk of getting cut on a glass bottle vs. a slight chance of a life-threatening disease/illness from a plastic bottle. But, there are easy, time-efficient and cost-effective ways to reduce the risk from harmful chemical exposure. There's no reason not to utilize them if you can. Also, there are manufacturing alternatives to biphenols and phthalates to make plastic do what we want.

Lastly it's a public health issue. A whole generation of peoples getting diseases from low-level chemical exposures and you now have a weakened, at-risk population, more costly and longer term healthcare issues and lowered mortality rates.

Getit.
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#38 Sep 18 2008 at 8:27 AM Rating: Decent
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Elinda wrote:
Lastly it's a public health issue. A whole generation of peoples getting diseases from low-level chemical exposures and you now have a weakened, at-risk population, more costly and longer term healthcare issues and lowered mortality rates.


More than one generation of people have been driving. ZOMG CARZ AR A HELTH RIX!
#39 Sep 18 2008 at 8:28 AM Rating: Default
MentalFrog wrote:

Ever tried explaining physics to a two year old? It's a waste of time.


Yes, because I'm SURE your opposing viewpoint on this subject is so solid, that I would have no way to understand it.

Why not just admit you don't like me for some reason, and keep it at that? You obviously have no actual rhetorical argument to back up what you're saying. You may not agree with my viewpoint, but that doesn't make it idiotic. In fact, just blindly saying I'm an idiot without anything to back it up is more idiotic than anything I said.

So, let me get this straight, you're saying that it's idiotic to believe that getting all riled up about plastic baby bottles is pretty redundant when the same people who worry about plastic baby bottles will subject their child to things far more dangerous anyway? Like driving in a car, or hell...breathing city air?

Please. If you disagree with my viewpoint, at least have the balls to back up your insults with..I dunno...reasons.



Or you can just hide behind the hackneyed "Oh, I would explain why, but you're too dumb to understand" argument that 11 year olds use.



Edited, Sep 18th 2008 12:25pm by DaimenKain
#40 Sep 18 2008 at 8:29 AM Rating: Good
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Elinda wrote:
Lastly it's a public health issue. A whole generation of peoples getting diseases from low-level chemical exposures and you now have a weakened, at-risk population, more costly and longer term healthcare issues and lowered mortality rates.
I see this as a bonus to my CPP investments. (Canadian Pension Plan)
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#41 Sep 18 2008 at 8:30 AM Rating: Decent
Skelly Poker Since 2008
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MentalFrog wrote:
Elinda wrote:
Lastly it's a public health issue. A whole generation of peoples getting diseases from low-level chemical exposures and you now have a weakened, at-risk population, more costly and longer term healthcare issues and lowered mortality rates.


More than one generation of people have been driving. ZOMG CARZ AR A HELTH RIX!
Well, they are a risk. That's why there are regulations on seat-belts, air-bags, stability, etc.

We don't just turn our heads away from safety concerns because there are other, perhaps greater, risks to a kid in a crib somewhere.
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#42 Sep 18 2008 at 8:32 AM Rating: Good
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DaimenKain wrote:

Or you can just hide behind the hackneyed "Oh, I would explain why, but you're too dumb to understand" argument that 11 year olds use.


Smiley: lol

You get 11 year olds telling you that? Smart kids.
#43 Sep 18 2008 at 8:34 AM Rating: Decent
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DaimenKain wrote:

Why not just admit you don't like me for some reason, and keep it at that?



And of course I don't like you, I never denied that. But I have no idea who the hell you even are.
#44 Sep 18 2008 at 12:41 PM Rating: Decent
Aripyanfar wrote:
yossarian wrote:
Aripyanfar wrote:
Youssarian, try searching for "endocrine disrupter/s" instead, then.


Okay. "An endocrine disrupter is defined as “an exogenous substance that causes adverse health effects in an intact organism, or its progeny, consequent to changes in endocrine function” [8]. EDCs constitute, therefore, a class of substances which is not defined by chemical nature but by biological effect [9]. Thus, a wide variety of pollutants which have been reported to disrupt normal pathways in animals, including pesticides [10], polycyclic aromatic hydrocarbons [11], phthalate plasticizers [12], certain polychlorinated biphenyls, dioxins, furans, alkylphenols, synthetic steroids, and natural products such as phytoestrogens, are collectively referred to as EDCs [1, 13 and 14]."

This is from an article by: Maria J. López de Alda and Damià Barceló in Journal of Chromatography A, an article I picked at semi-random.

This is not just plastics, but a broad variety of chemicals. Will follow up later when I have more time.

*nod nod*

That's the stuff. Or class of stuff, perhaps?


It is a definition of an effect. Some chemicals may cause said effect, and there is good evidence that some do. The chemicals need not have any similar chemical background.

The term endocrine disrupting compound, sometimes abbreviated EDC, is like carcinogen: that which causes cancer. Anything could be a carcinogen. It is exceptionally difficult to predict ahead of time which. Testing everything is impracticable. It is one of many things to be concerned with. I'm not convinced it is more prevalent then cancer, although more study may help. There are probably many other pathways to ill health in humans.

This is what I've learned:

(1) some plastics contain specific EDC's.

(2) under some conditions, those EDC's can be released into the environment

(3) even in rather small concentrations, less then currently recommended levels of tolerance (not all nations have any recommendations of any kind), some EDC's do have adverse effects on fish, through mechanisms which make it likely that similar effects will follow for humans.

I do not know:

(4) do plastics necessarily contain these, or is it an additive?

(5) the magnitude of effect on human health

(6) the amount of leaching due to normal human use.

From: Endocrine disruption caused by two common pollutants at “acceptable” concentrations
by:
Lucia Magliuloa, Martin P. Schreibman, Jessica Ceprianoc and Jacquline Lingd
Neurotoxicology and Teratology Volume 24, Issue 1, January-February 2002, Pages 71-79.

Aripy wrote:
In biological science endocrine disrupters are also known as xenohormones, (foreign hormones) particularly because they are chemicals that come from the outside environment into a human or animal body, and act on the hormone system, instead of being generated inside the human or animal body.


Maybe, but not much in the scientific literature.

Aripy wrote:
In the last 60 years or so, there's been an enormous upswing of xenohormones released into the environment and used as consumer products from synthetic chemical/crude oil sources, which has coincided with a huge upswing in some pathologies. The correlation has made a lot of biological scientists very nervous, and there's been a lot of studies investigating causative links. So lobbyists are focusing on asking regulators to investigate and regulate xenohoromones/endocrine disrupters of synthetic/crude oil origin.


I doubt that there was a good baseline 60 years ago. Potentially, in heavily industrialized areas such as London, it could have been worse. Coincidence with some pathologies? People are living longer, thus revealing many more pathologies. It would be very, very hard to pin any such upswing on any single class of chemical, or vaccine, for example.
#45 Sep 18 2008 at 1:36 PM Rating: Good
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Nadenu wrote:
Quote:
Tare wrote:
Quote:

Debalic wrote:
Speaking of which, he got a right nasty bump on his forehead so we haven't been taking many pictures. Poor lil fella.



Huh. Mia was at least 2 before we started beating her.



You're both slackers. I was getting punched in the gut before they were born!


Nads, truly, you are all woman.


edited to add: And congrats on 10k!

Edited, Sep 18th 2008 4:31pm by Yanari
#46 Sep 18 2008 at 6:05 PM Rating: Good
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Yanari wrote:

edited to add: And congrats on 10k!


Thank ya! Took me long enough, haha
#47 Sep 18 2008 at 11:11 PM Rating: Good
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yossarian wrote:
a lot of stuff


Some plastics ARE EDCs, some are not. There are a lot of concerned people now that think we should be systematically going through and testing materials for whether they are an EDC or not. This is not a consumer protection movement that has it's origins with "ordinary people". This is a lobbying movement by scientists who have been appalled by what their studies find, who have gone to politicians directly, and have also started trying to publicize their findings more directly to ordinary people, to start a broad-based public and consumer movement, to get some new government health-protective regulations. The book Our Stolen Future is part of the effort by some scientists to raise public awareness of the issue.

I first became aware of the EDC/Xenohormone issue about 10 years ago, listening to my radio station, where a scientist was being interviewed. I don't remember his name from this distance, but he was using the word xenohormone to describe something that he was concerned about. I wanted to find out more, the only thing I tracked down at the time was a book on reproductive health in women. Which was actually useful for me in other ways, but not totally informative about the whole EDC thing. I heard more about EDCs on the radio about a year later, I subsequently tracked down Our Stolen Future, which to this day has given me the most wide-ranging and in-depth knowledge that I have on the issue. I am of course, a layperson, having never done science past first-year uni electives. The issue barely turned up in the media in Australia, until the last two years there has been an explosion of hour-long documentaries on the issue, from Britain and America, as well as Australia. The subject also turns up more often than it used to on current affairs shows both on TV and radio. The documentaries and interviews that I have seen lately don't mention Our Stolen Future, or the authors of that book, but the science that they are presenting all still agrees what I read in that book, so it's still my major text for the subject.

Right at this moment, the issue looks pretty much exactly like the earlier stages of the "Smoking causes lung-cancer issue." In the 1930s and 1950s, scientists and cigarette company executives knew cigarettes caused lung cancer. But it took a long time for that knowledge to filter down to the public and the politicians, and for anything to done about it.

The good thing about this particular issue is that for every material that is an EDC, there's another material that can get the job done just as well, that isn't an EDC.

The way that one student scientist discovered the issue of EDCs is that suddenly ALL of her breast-cancer tissue samples for her Doctorate paper started growing in their plastic petri-dishes, regardless of whether she had added a strong oestrogen to the dishes or not. She was going mad trying to exclude everything from her lab, until she finally rang up the petri-dish manufacturer, and asked if they had changed the plastic they made their dishes out of, and which batch was the turn-over point? Sure enough the manufacturer had changed the plastic formula for the dishes, and the change-over coincided with her experiments going wrong and staying wrong. The old plastic dishes wouldn't automatically make breast tumor tissue grow in the presence of it, the new plastic would.

So we have an example here of one type of plastic that is hormonally active, and another plastic that is identical functionally for consumer use that is not hormonally active. We aren't going to have to outlaw or phase out all plastics, and all additives. We are just going to have to outlaw and phase out some of them.

Yes, it's likely to be a long process. That doesn't mean that it's not worth doing. Some EDCs are as fully catastrophic and/or long lasting in their adverse effects as lead-poisoning or Asbestos
#49 Sep 25 2008 at 3:27 AM Rating: Good
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Nobby wrote:
Our children get teh pale and toothless, someday Yanks will eat them.
Fixereded.
#50 Sep 25 2008 at 3:32 AM Rating: Good
#51 Sep 25 2008 at 5:37 AM Rating: Good
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catwho, pet mage of Jabober wrote:

That last link made me ecstatic. I really hope that they have some control over the bacteria, that it's only going to grow, when and where they want it to grow. I don't like the thought of escaped wild strains sitting around waterways growing plastic. But if that's not a potential problem, then this is a VERY good thing.

It's a solution to one of the problems from the inevitable end of the supply of natural crude oil. It's also manufacturing a current product at the same price using 30% less energy, which is of course a major and important benefit.
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