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#1 Sep 16 2008 at 9:31 AM Rating: Excellent
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A crap load of health problems, that is.

FDA backs BPA as study links it to heart disease, diabetes

Quote:
For the first time, a large, population-based study links a chemical in plastic baby bottles to heart disease and diabetes in humans.

Some scientists say the study — released today to coincide with a Food and Drug Administration meeting— shows that bisphenol A, or BPA, is too dangerous to allow in consumer products, especially those used by babies and pregnant women.

U.S. government regulators on Tuesday defended their assessment that BPA is safe.

"A margin of safety exists that is adequate to protect consumers, including infants and children, at the current levels of exposure," Laura Tarantino, a senior Food and Drug Administration scientist, told an expert panel that has been asked for a second opinion on the agency's assessment of BPA.

FDA officials said they are not dismissing such findings, and conceded that further research is needed. "We recognize the need to resolve the concerning questions that have been raised," said Tarantino. But the FDA is arguing that the studies with rats and mice it relied on for its assessment are more thorough than some of the human research that has raised doubts.

The FDA last month released a draft report concluding that BPA doesn't pose a risk at the levels to which people are exposed every day. That puts the agency at odds with the National Toxicology Program, which this month expressed "some concern" that BPA alters behavior, the brain and prostate gland in children, both before and after birth.


The article is longer than that, that's just the intro...

I'm not overly concerned since I'm one who breastfeeds (and that seems to be the major source of "OMGITSPOISON!"), but I'm all for getting rid of as many unnecessary chemicals as possible.../shrug Anyway, thought some of the rest of you may be interested.

Nexa
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#2 Sep 16 2008 at 9:37 AM Rating: Good
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Sounds like this is right up Ari's alley.
#3 Sep 16 2008 at 9:52 AM Rating: Decent
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My daugher, after years of being told not to put this or that in her mouth (she was warned away from most any plastic stuff), now sarcastically asks me if it's ok to lick her linoleum floor or suck on her ipod (I can only assume it's in a plastic case of some sort).

An interesting note: The EU banned many of the worst plasiticizers from childrens and baby products 5 or 6 years ago. Consequently much of the stuff that couldn't be sold there has come to the US and is sold, mostly, at the discounty Dollar Store type places.





Edited, Sep 16th 2008 7:51pm by Elinda
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#4 Sep 16 2008 at 9:56 AM Rating: Good
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Plastics appear to be the cause of a lot of the chronic maladies that are cropping up nowadays. Its like pewter back in the dark ages: everyone uses it, its convenient, and it will be tough to adjust to not using it as much. I think they should switch to a lot more glass use. Glass is easily recycled, and is made of natural materials that are not harmful to the body (except on a short-term physical basis if you get cut by it).
#5 Sep 16 2008 at 10:24 AM Rating: Decent
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AshOnMyTomatoes wrote:
Plastics appear to be the cause of a lot of the chronic maladies that are cropping up nowadays. Its like pewter back in the dark ages: everyone uses it, its convenient, and it will be tough to adjust to not using it as much. I think they should switch to a lot more glass use. Glass is easily recycled, and is made of natural materials that are not harmful to the body (except on a short-term physical basis if you get cut by it).


I'm not giving my 1 year old a glass bottle.
#6 Sep 16 2008 at 10:28 AM Rating: Good
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Elinda wrote:
The EU banned many of the worst plasiticizers from childrens and baby products 5 or 6 years ago. Consequently much of the stuff that couldn't be sold there has come to the US and is sold, mostly, at the discounty Dollar Store type places.
Our children get teh smart and healthie, Yank trailer-trash accelerate darwinism.

win:win Smiley: nod
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#7 Sep 16 2008 at 10:34 AM Rating: Decent
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Yodabunny wrote:
AshOnMyTomatoes wrote:
Plastics appear to be the cause of a lot of the chronic maladies that are cropping up nowadays. Its like pewter back in the dark ages: everyone uses it, its convenient, and it will be tough to adjust to not using it as much. I think they should switch to a lot more glass use. Glass is easily recycled, and is made of natural materials that are not harmful to the body (except on a short-term physical basis if you get cut by it).


I'm not giving my 1 year old a glass bottle.
I did, but was mostly always around when they had bottles. Yes they could break if thrown but it would be out of range of the high chair, or whatever. I honestly can't think of an instance where one was broken by one of the kids though. Glass bottles were hard to find however. I also used a nice soft rubber pacifier for one of them though - it's all a matter of risk eh;)

I think the biggest thing to be aware of is that any of the suspected 'bad' actors, will be more likely to leach from the product if it is heated. So, if you want to use plastic bottles, don't put warm milk in it. Don't heat foods in the microwave in plastic containers or plastic wrap. You shouldn't, btw, let a baby go to sleep with a bottle of anything other than water - can be bad for teeth and gums.

You can easily find products these days that are free of BPA and phthalates if you look around.
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#8 Sep 16 2008 at 10:36 AM Rating: Decent
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Nobby wrote:
Elinda wrote:
The EU banned many of the worst plasiticizers from childrens and baby products 5 or 6 years ago. Consequently much of the stuff that couldn't be sold there has come to the US and is sold, mostly, at the discounty Dollar Store type places.
Our children get teh smart and healthie, Yank trailer-trash accelerate darwinism.

win:win Smiley: nod
Still trying to get back at us over the whole tea-bag thing, eh.

Coffee > tea.
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#9 Sep 16 2008 at 10:51 AM Rating: Excellent
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Elinda wrote:
Nobby wrote:
Elinda wrote:
The EU banned many of the worst plasiticizers from childrens and baby products 5 or 6 years ago. Consequently much of the stuff that couldn't be sold there has come to the US and is sold, mostly, at the discounty Dollar Store type places.
Our children get teh smart and healthie, Yank trailer-trash accelerate darwinism.

win:win Smiley: nod
Still trying to get back at us over the whole tea-bag thing, eh.

Coffee > tea.


<insert Jophiel Boston Tea Party GIF Here>

Nexa
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#10 Sep 16 2008 at 10:55 AM Rating: Good
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Something tells me that I'm likely to feed them worse things as they grow up, such as McD's (or any fast food), children's marketed food, etc...


I might pay a little more attention to this once it gets past "linked to" status.

Edited, Sep 16th 2008 3:50pm by Uglysasquatch
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#11 Sep 16 2008 at 11:02 AM Rating: Excellent
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Uglysasquatch, Mercenary Major wrote:
Something tells me that I'm likely to feed them worse things as they grow up, such as McD's (or any fast food), children's marketed food, etc...


I might pay a little more attention to this once it gets past "linked to" status.



A guild mate of mine in EQ used to put macaroni and cheese into a McDonald's box to fool his four-year-old into eating it.

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#12 Sep 16 2008 at 11:04 AM Rating: Good
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Nexa wrote:

<insert Jophiel Boston Tea Party GIF Here>

Nexa
One of the most moving pictures ever posted here.

Nexa
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#13 Sep 16 2008 at 11:05 AM Rating: Good
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Samira wrote:
A guild mate of mine in EQ used to put macaroni and cheese into a McDonald's box to fool his four-year-old into eating it.

I don't throw out food, it's not in me, which means I'd have ot eat it first to get the empty box. This greatly limits what box could be used.
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#14 Sep 16 2008 at 11:07 AM Rating: Decent
Elinda wrote:
Nobby wrote:
Elinda wrote:
The EU banned many of the worst plasiticizers from childrens and baby products 5 or 6 years ago. Consequently much of the stuff that couldn't be sold there has come to the US and is sold, mostly, at the discounty Dollar Store type places.
Our children get teh smart and healthie, Yank trailer-trash accelerate darwinism.

win:win Smiley: nod
Still trying to get back at us over the whole tea-bag thing, eh.

Coffee > tea.


You only think that because your coffee is full of salt.
#15 Sep 16 2008 at 11:15 AM Rating: Decent
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Kavekk wrote:


You only think that because your coffee is full of salt.
Salt is good. (but it's not in my coffee)
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#16 Sep 16 2008 at 12:00 PM Rating: Decent
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If I were more of the tinfoil hat disposition, I'd say the BPA hysteria is being generated by the plastic manufacturers to force us to spend money on overpriced BPA-free replacements of stuff we already own.

And yes, I got rid of my BPA bottles. Babies-R-Us was taking them back and giving store credit when you turned in the BPA-containing bottles, so I took all my bottles in. Even though I'd bought them separately, they would only refund me the price of having purchased them in a 3-pack.

Avent is the brand of bottle I was using, but apparently it's a popular enough brand that now that Avent has come out with BPA-free bottles, they can't keep them on the shelf. So I had to get the Born Free bottles, which are about the same price as the Avent bottles (when they are in stock) but have a much more complicated venting system. And to top it all off, the BPA-free bottles are about twice the price of the old bottles. A single old-style Avent bottle is around $6--the BPA-free version is $11. A 3-pack of the 11oz old-style bottles was $13, a 2-pack of the 8oz BPA-free bottles (apparently they are no longer making 11oz bottles, nor is Avent packaging them in 3-packs any longer) is $19.

What's more, the store credit can only be used for purchasing bottles. So it's not like I could decide I would make do with his stainless-steel sippy bottle and use the store credit on a couple new pairs of pajamas for the winter. Nope, I took in four 4oz bottles, five 8oz bottles and three 11oz bottles and emerged with three 8oz bottles and enough credit for two more if I ever catch them when they are restocked.

This is where the [::motz::] smiley would be if I had premium.

(and yes, he is still about 50% breastfed, but he gets a bottle in the evening to fill in the empty corners and also he gets bottles when someone else is watching him.)

Edited, Sep 16th 2008 12:58pm by Ambrya
#17 Sep 16 2008 at 1:03 PM Rating: Decent
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Ambrya wrote:
[link=http://www.kleankanteen.com/2products/klean-kanteen-sippy.html]


That factory/warehouse is a pain to get shipments out of, no-one wants to drive up into the mountains to pickup a skid or two, no-one...they seriously didn't think that location through.
#18 Sep 16 2008 at 3:15 PM Rating: Good
AshOnMyTomatoes wrote:
Plastics appear to be the cause of a lot of the chronic maladies that are cropping up nowadays.


No, they don't.

BPA is a coating put on plastics and metals. It is analogous to lead in glass in this sense: it is not necessary and both seem to be dangerous, although the danger of lead is quite well known, our glorious leader in the US appointed a pediatrician who literally did not believe in lead poisoning to a position of prominence within the regulatory apparatus, as I posted here at that time.

The truth is complex, and requires study. Glass, plastic, stainless steel: probably fine but the coatings upon them may kill you...best not to oversimplify when dealing with what is effectively medical advice.
#19 Sep 16 2008 at 8:14 PM Rating: Good
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There is a designator on the bottles, a Triangle with a 7 in the midle I believe? When I saw this study on the news this evening, I went straight for my bottles. None of them have it so I dont have to take them back.
#20 Sep 16 2008 at 9:53 PM Rating: Good
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If this issue concerns or just interests you, the best starting point I know about is the book called Our Stolen Future, by Colborn, Dumanoski and Peterson. (Two scientists and a reporter.) The book is simply written, for laypeople, and set out as a narrative about some real-life people as a hook for talking about scientific discoveries, so it's an interesting read that doesn't bore you half way through. For people who like to know that they are getting REAL information, the last 33 pages of Notes are devoted to a reference list of original sources in Peer-reviewed science and medical journals and stand-alone published studies. Our Stolen Future has a related website with links to many articles and studies, here. I recommend bookmarking it for later perusal if you are interested in the subject, it's too large to take in all at once.

The broad issue is about Xenohormones, small, fat-soluble molecules that have chemical structures close to human and animal hormone molecules. Xenohormones are sometimes very problematic because their "close but not exact" mimicking of human/animal hormones means that they are highly reactive inside humans and animals, but don't do the job that hormones are supposed to do properly, leading to a wide range of health and fertility problems. There is now a concern that a large percentage of chemicals derived from Crude oil are xenohormonal in nature.

The biggest new scientific concern is that it now turns out that the health problems of synthetic chemicals don't scale up in a linear way with the size of the dose, as was previously thought. So that present regulations for the cutoff point for safe, allowable concentrations of a chemical may actually be hopelessly inadequate.

There IS something that can be done about this. Individual products don't need to be tested, but individual materials (that are derived from crude oil) should all be tested for xenohormonal activity via fast standardised pathology tests. Materials that fail the tests should be banned from future manufacture and sale, in the same way that DDT and asbestos are now banned. An example of how a material might be tested for xenohormonal activity is a test that determines if a material is a xenoestrogen (acts like oestrogens in humans and animals.) The material is put in a petri-dish with some breast-cancer cells. If the breast-cancer cells multiply and grow, the material is a strong xenoestrogen.

After a period of years, perhaps decades, of going through all crude-oil derived materials, we'll have a suite, a long list, of materials that are hormonally safe for humans to use, and safe to dispose of into the environment, and a suite of now banned substances. Not all plastics and not all synthetic food and bathroom product additives are xenohormones. The problem for today's consumers is we don't know which ones are and which ones aren't. There may possibly also be a third suite of allowed substances that come with a safety rule of no human skin contact, or ingestion.

If you would like to do something personal about the issue, after deciding for yourself whether this is all a crock of **** or not, you could write or email to your political Representative, saying, "I am concerned about the issue of Xenohormones, and I would like all crude-oil derived materials to be tested for Xenohormonal activity, and I would like all crude-oil derived materials that turn out to be hormonally active to be banned from future manufacture or sale."

As for glass baby bottles, they were used for decades all over the world. The biggest advantage of plastic baby bottles when they arrived was not that they noticeably broke less often, but that they were noticeably lighter than the glass bottles.

If you don't like the idea of glass, go with something else (that isn't coated in a plasticizer.) Personally, I wouldn't go with any plastic for a baby that hasn't been tested for xenohormonal activity.

Edited, Sep 17th 2008 1:55am by Aripyanfar
#21 Sep 17 2008 at 4:10 AM Rating: Decent
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My wife brought this to my attention a few weeks ago. We use the Avent bottles for Thom. Hope it's not making him retarded.

Speaking of which, he got a right nasty bump on his forehead so we haven't been taking many pictures. Poor lil fella.
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#22 Sep 17 2008 at 4:20 AM Rating: Good
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Debalic wrote:
Speaking of which, he got a right nasty bump on his forehead so we haven't been taking many pictures. Poor lil fella.


Huh. Mia was at least 2 before we started beating her.
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#23 Sep 17 2008 at 4:35 AM Rating: Good
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Tare wrote:
Debalic wrote:
Speaking of which, he got a right nasty bump on his forehead so we haven't been taking many pictures. Poor lil fella.


Huh. Mia was at least 2 before we started beating her.


You're both slackers. I was getting punched in the gut before they were born!
#24 Sep 17 2008 at 7:44 AM Rating: Decent
Aripyanfar wrote:


The broad issue is about Xenohormones, small, fat-soluble molecules that have chemical structures close to human and animal hormone molecules.


pubmed turns up seven entries for xenohormone and it's plural. That is quite low. I read the one by Davis Telang Osborne and Bradlow (I think it should be free for anyone to read online, just google pubmed, follow link, search for xenohormoes (plural), it should turn up). I did not read the other six, but this one is basically a pure hypothesis paper, no data, just a possible pathway. That doesn't mean it is wrong.

Edit: searching pubmed for bisphenol A turns up 4778 entries. BPA turns up just under 2000.

Edited, Sep 17th 2008 8:45am by yossarian
#25 Sep 18 2008 at 6:05 AM Rating: Good
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Youssarian, try searching for "endocrine disrupter/s" instead, then.

I don't have the facilities to upload the book's reference list, so maybe you could have a look at some of these studies which concern xenohormones/endocrine disrupters instead (you might recognise already known dangerous and banned substances in this list, what you night not know is that these substances are dangerous or carcinogenic in part because they are xenohormones/endocrine disrupters AS WELL as powerful oxidants or whatever):

Quote:
Cancer

* Early DDT exposure linked to breast cancer later in lifenew
* Bisphenol A interferes with treatment for prostate cancernew
* Bisphenol A causes breast cancer in ratsnew
* Bisphenol A increases sensitivity to carcinogen that causes breast cancer new
* Epigenetic inheritance of adult chronic diseases, including tumorsnew
* Bisphenol A tied to prostate cancer in rats
* Bisphenol A alters mammary gland development in mice
* Genotype increases breast cancer risk associated with PCBs
* Testicular cancer linked to environmental exposures early in life
* Are current declines in non-Hodgkin's lymphoma rates tied to chemical bans in the '70s?
* Mother's organochlorine contamination linked to son's testicular cancer
* Cancer and EDCs: are we asking the wrong question in human studies?
* Miscalculation revealed: we are not winning the war on cancer after all
* Bisphenol A stimulates proliferation of prostate cancer cells
* Seveso, Italy: breast cancer risk rises with dioxin exposure
* Childhood leukemia linked to household pesticides
* A 2001 review of breast cancer epidemiology
* Soy phytoestrogen causes uterine cancer, like diethylstilbestrol (DES)
* Low-level ******* interferes with glucocorticoid's role in tumor suppression
* PCBs interact synergistically with virus to elevate risk of non-Hodgkin's lymphoma
* Dieldrin associated with increased risk of breast cancer
* Dieldrin linked to higher mortality rates in breast cancer victims




Behavior and intelligence



* Low doses of BPA alter sexual dimorphism in brain structure and behavior in mice
* Low doses of bisphenol A alter maternal behavior in mice
* A single low exposure to PBDE in the womb causes ADHD in pubertal rats
* Brain development patterns different for autistic children, starting in the womb
* High PBDE levels in California and Indiana
* 10-fold higher rate of autism in Atlanta found by CDC study
* Evidence builds that soaring autism rate in California is not an artifact
* ADHD associated with smaller brain size in children
* Dioxin and PCBs alter sex-specific behavior in children
* Dioxin at extremely low levels reduces motivation in rats
* Low level carbaryl disrupts frog behavior
* Brominated flame retardant disrupts "brain growth spurt" in mice
* Polybrominated flame retardants are powerful thyroid disrupters
* Nonylphenol alters dopamine uptake in hypothalamic cells in nonmontonic fashion
* Brominated flame retardants act as developmental neurotoxicants in mice



Endometriosis

* Strong links apparent in animal studies of dioxin and endometriosis
* Immune and endocrine disorders much more likely in women with endometriosis




Sperm count and other testicular maladies

* Phthalate linked to reduced sperm quality in men
* Phthalate levels linked to genital abnormalities in boys
* A single low exposure to PBDE in the womb reduces adult sperm count
* Dramatic link between sperm quality and pesticide exposure in mid-west men
* Phthalate levels linked to deterioration in ***** quality
* PCB congener levels linked to deterioration in ***** quality
* Phthalate exposure associated with DNA damage in men's sperm
* Big geographic differences in sperm quality among US men
* Testicular dysgenesis syndrome: linking testicular cancer, hypospadias, cryptorchidism and lower sperm quality to a common origin
* Are sperm maladies contributing to fertility declines?
* Cryptorchidism linked to estrogenic organochlorine exposure
* Genetic basis of endocrine disruption leading to cryptorchidism
* Expanded data set corroborates broad-based decline in sperm count
* Dramatically low levels of sperm count prevalent in young Danish men. This study is the best attempt at a representative sample of a population yet obtained in studies of human sperm count.
* PCBs exposure in the womb leads to lower sperm quality




Reproduction and fertility

* New CDC data confirm ubiquitous exposure to bisphenol Anew
* Neonatal BPA exposure causes uterine abnormalities in middle-aged mice, like DESnew
* BPA scrambles the chromosomes of grandchildren in micenew
* Testosterone is declining in Massachusetts men
* Epigenetic inheritance of adult chronic diseases, including testicular dysfunction
* Bisphenol A linked to recurrent miscarriage in people
* Bisphenol A alters mammary gland development in mice
* Low dose effects on prostate development confirmed and extended
* Several xenoestrogens stimulate prolactin secretion at extremely low levels
* Risks of infertility higher in women using herbicides and fungicides
* Phthalate linked to preterm birth
* Research links herbicides used on wheat to birth defects in the Great Plains
* DDT in mother's serum linked to more difficulty for daughter to become pregnant, 30 yrs later
* Plastic compound causes chromosomal error that in people leads to miscarriage, Down Syndrome
* Common lawn herbicide mixture causes fetal loss in mice at very low exposure level
* Frog reproductive development is disrupted by extremely low levels of atrazine.
* DDT linked to preterm birth. May have caused 15% of infant mortality in US during the 1960s.
* A compilation of impacts of contamination on the timing of puberty in animals
* Pregnant women living within a few miles of fields where agricultural pesticides are used are at increased risk of losing their fetus
* DES daughters are more likely to have bad pregnancy outcomes, including increased rates of spontaneous abortion
* Eating contaminated fish impairs conception in women living around the Great Lakes
* Polybrominated biphenyls in utero associated with early menstruation




Immune system

* Phthalate tied to asthma in human study new
* Phthalate increases allergic reaction in mice at low exposure levels new
* Epigenetic inheritance of adult chronic diseases, including immune dysfunction
* Pesticide mixture suppresses tadpole immune system, causes infection new
* Do phthalates cause asthma via endocrine disruption?
* Immune system impacts of dioxin linger for decades
* Low-level ******* interferes with glucocorticoid and may undermine immune system function
* Children with higher (but still low) background exposure to PCBs suffer increased rates of childhood diseases
* PCBs interact synergistically with virus to elevate risk of non-Hodgkin's lymphoma





Wildlife and ecosystem

* Pesticide mixture suppresses tadpole immune system, causes infection new
* Low doses of nonylphenol have profoundly adverse effects on oysters
* Atrazine induces gonadal abnormalities in wild frogs at very low levels
* Pesticides render frog immune system less able to resist deformity-causing parasite
* Frog malformities linked to parasites in American west
* Frog reproductive development is disrupted by extremely low levels of atrazine.
* Nitrogen fixation of plants disrupted by EDCs
* Salamander behavior disrupted by low level endosulfan
* Frog behavior disturbed by low level carbaryl
* Widespread feminization of wild Chinook salmon in the Columbia River
* Orca (killer whales) in British Columbia, Canada, heavily contaminated with PCBs
* Endocrine disruption by nonylphenol interferes with osmoregulatory change in Atlantic Salmon, contributing to their endangerment.
* Salmon transport persistent bioaccumulative contaminants up-river during their migrations
* A single dose of DDT during development causes complete sex reversal in medaka, a species of fish. Chromosomal males become fertile females.





Low dose effects

* New CDC data confirm ubiquitous exposure to bisphenol Anew
* Scientists warn policymakers about adverse effects of bisphenol Anew
* Does the 'dose make the poison?'new
* BPA scrambles the chromosomes of grandchildren in micenew
* DEHP alters a brain enzyme important to male masculinization
* DEHP heightens allergic response in mice in non-monotonic fashion at low doses
* Bisphenol A increases sensitivity to carcinogen that causes breast cancer
* Bisphenol A tied to prostate cancer in rats
* Pesticide mixture suppresses tadpole immune system, causes infection
* Industry science on low doses effects of bisphenol A profoundly flawed
* Low doses of Bisphenol A cause insulin resistance in mice
* Scientists challenge irresponsible use of hormesis to loosen health standards
* Extremely low doses of Bisphenol A alters mammary gland development in mice
* Low dose effects on prostate development confirmed and extended
* Low doses of BPA alter sexual dimorphism in brain structure and behavior in mice
* Low doses of bisphenol A alter maternal behavior in mice
* Several xenoestrogens are as powerful as estradiol via cell membrane receptor
* Cadmium provokes estrogenic responses at extremely low levels of exposure
* Bisphenol A equipotent with estradiol in activating key gene transcription factor at <1ppb
* Analysis concludes high level testing cannot be used to detect low level effects
* Atrazine induces gonadal abnormalities in wild frogs at very low levels
* Common lawn herbicide mixture causes fetal loss in mice at very low exposure level
* Bisphenol A at nanomolar levels stimulates prostate cancer cell proliferation
* Frog reproductive development is disrupted by extremely low levels of atrazine
* Extremely low level dioxin undermines rat behavior
* Controversial low-dose impacts of bisphenol A on prostate confirmed independently
* Lab experiments find low level DDT and HCH exposure cause adverse effects in mice
* DDE and HCH found in amniotic fluid of 1/3rd of Los Angeles women measured
* Strains of mice differ dramatically in their genetic susceptibility to endocrine disruptors. One of the most widely used strains in tox testing is surprisingly insensitive, and thus inappropriate to use in establishing health risks.




Results important for regulatory science

* Scientists warn poiicymakers about adverse effects of bisphenol Anew
* With a non-monotonic dose-response curve, DEHP alters a brain enzyme important to male masculinization at environmental levels new
* DEHP heightens allergic response in mice in non-monotonic fashion at low doses
* Epigenetic inheritance of adult chronic diseases across multiple generations
* Pesticide mixture suppresses tadpole immune system, causes infection
* Analysis concludes high level testing cannot be used to detect low level effectsLab contamination from polycarbonate plastic likely to have misled research
* Atrazine induces gonadal abnormalities in wild frogs at very low levels








Mixtures of chemicals

* Pesticide mixture suppresses tadpole immune system, causes infection
* Common lawn herbicide mixture causes fetal loss in mice at very low exposure levelWeak xenoestrogens combine to have strong effects
* Even weak xenoestrogens can have additive effects in the presence of 17ß-estradiol
* Nitrate interacts with pesticides to produce unpredictable results in mice at levels often found in US drinking supplies, including increases in aggression. Strong synergy detected between PCBs and dioxin
* PCBs interact synergistically with virus to elevate risk of non-Hodgkin's lymphoma




Ubiquity of exposure

* New CDC data confirm ubiquitous exposure to bisphenol Anew
* Scientists warn policymakers about adverse effects of bisphenol Anew
* Bisphenol A ubiquitous in Americans
* Teflon-related chemicals found in people on 5 continents
* High levels of polybrominated flame retardants in American mothers and fetuses
* Nonylphenols ubiquitous in consumer food
* Brominated flame retardants common in sewage sludge used on farmland
* Phthalate exposure widespread in American public
* PCB exposure in remote Arctic is up to 70x higher than in areas closer to source of contaminant.
* POPs carried by transpacific winds to the west coast of North America
* Dioxin in Canadian arctic linked to specific sources to the south


Edited, Sep 18th 2008 10:09am by Aripyanfar
#26 Sep 18 2008 at 7:20 AM Rating: Good
Aripyanfar wrote:
Youssarian, try searching for "endocrine disrupter/s" instead, then.


Okay. "An endocrine disrupter is defined as “an exogenous substance that causes adverse health effects in an intact organism, or its progeny, consequent to changes in endocrine function” [8]. EDCs constitute, therefore, a class of substances which is not defined by chemical nature but by biological effect [9]. Thus, a wide variety of pollutants which have been reported to disrupt normal pathways in animals, including pesticides [10], polycyclic aromatic hydrocarbons [11], phthalate plasticizers [12], certain polychlorinated biphenyls, dioxins, furans, alkylphenols, synthetic steroids, and natural products such as phytoestrogens, are collectively referred to as EDCs [1, 13 and 14]."

This is from an article by: Maria J. López de Alda and Damià Barceló in Journal of Chromatography A, an article I picked at semi-random.

This is not just plastics, but a broad variety of chemicals. Will follow up later when I have more time.
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