Since I met online several ME* patients from the UK, I've learn to question studies done in the UK so I went looking for the study to see what more I can learn.
The full study can be found at http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371%2Fjournal.pmed.0050045#toclink3
Medline article quote, states a fact that I known for years.
Quote:
Dr. Nada Stotland, president-elect of the American Psychiatric Association, said she wasn't surprised that the study found that not every antidepressant works for every patient. Many people who are depressed don't respond to the first antidepressant they try. It can take up to an average of three different antidepressants until one works for a particular patient, she said.
"Medication helps some, but not all, people with depression," Stotland said in a prepared statement. "For people with mild to moderate depression, psychotherapy can work as well as medication. Studies have shown that between 70 and 80 percent of people can and do get better with a combination of treatment approaches, which will often include individual therapy, family therapy and/or medication."
I have Major Depression Disorder and for 10 years been in treatment and on different medication for as well as talk therapy. I also had postpartum depression in 1984, which was treated with medication and day treatment for 16 months and short pout of depression in 1989 that I received talk therapy for.
I been in a day treatment program where I been going for treatment 7 of the last 10 years, but for one year the state felt I didn't need the program. I can go up to 3 days a week for a mixture of group and individual treatment sessions with my treatment team.
I wouldn't take medicines if I hadn't seen how much of a difference they can make for me. I long ago decided illegal drug use wasn't worth risk of losing custody of my children and dislike being tipsy, though I do enjoy a good beer or occasional glass of wine. So I'm one of the few people I know in day program who isn't co-dependent.
IF I have one big problem that treatment can't seem to help with, it's that I tend to talk far too much and forget to keep on subject. This is why I have a low post count. I hate finding myself making gbaji length posts. I will admit that I can be wrong and accept criticism of my faults.
rest of post is history of medication and and only mention to show evidence for my statement so far. I'm not an expert, but I do play one for those who let me take the floor instead of speaking up in group.
During the years I tried 3 different tricyclics, 3 SSRI's and one SNRI, as well as Xanax for panic disorder. Of all of the anti-depressants only imipramine (brand name: Tofranil) never worked at all. Amitriptyline and nortriptyline, both had side effects that my other doctors saw as a problem due to very dry eyes, so though they work I was taken off them by recommendation of my eye doctor.
OF the 3 SSRI's I taken;
* escitalopram (brand name: Lexapro) - taken less then 6 months then stop working
* fluoxetine (brand name: Prozac) - Work at higher doses, but stopped when diagnose with FMS, when I was put on Amitriptyline. I then went on Gabapentin since it was throught to help with stabilization of mood disorders as well as show to help with nerve pain.
* sertraline (brand name: Zoloft) - Did not work after 3 months for me.
SNRI - venlafaxine (brand name: Effexor) This has been the most effective of all anti-depressants and only when I show sign of Season Depression Disorder, did we go first to max dose and then add Prozac in a low dose.
For the last 5 plus years, I been taking the max dose of Effexor XR, though I had to start blood pressure medicine to deal with it's worst side effect. 10mg of Prozac. My Psychiatrist also prescribes my Gabapentin, though I only need it for the pain of my FMS. Effexor is also what my OB-GYN, says They would have given me for perimenopause, since I have family history of breast cancer. Only other medicine I take is for my cholesterol level and Ultram for pain. Problem is I tend to forget to take the cholesterol medicine with meals and prefer to use meditation for pain since it has no side effects, to deal with so may go several days without any pain medication.
Last time I had problem with panic attacks, I was given Xanax, but took only 2 out of the bottle of 30 with 1 refill. I find talk therapy less addictive and far safer.