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The drugs don't workFollow

#27 Feb 27 2008 at 10:36 AM Rating: Good
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I find good sex to be a great anti-depressant. Perhaps the problem with all these people is that they are not getting laid, and surprise, even after taking the pill they are still not getting any.
#28 Feb 27 2008 at 10:46 AM Rating: Decent
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fhrugby the Wise wrote:
I find good sex to be a great anti-depressant.
Indeed.

....and don't think it's not readily obvious who of you out there are not getting it enough or at all.
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#29 Feb 27 2008 at 11:18 AM Rating: Good
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fhrugby the Wise wrote:
I find good sex to be a great anti-depressant.
Smiley: nod

No clue if bad sex works too - I'll cross that bridge if I ever come to it Smiley: grin
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#30 Feb 27 2008 at 11:34 AM Rating: Good
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RedPhoenixxx wrote:
Overlord Demea wrote:
but they certainly do make drugs that work, or else they wouldn't be in business.


Yes and no. Most branded drugs have extremely marginal benefits compared to generic ones. Not only that, but drug companies are not forced to disclose all of their research, only the ones they want to disclose. The implications of this are huge.

Though I have to qualify this by saying that's how it works in the UK. Not sure if it's the same in the US.

This is easily solved by a change in legislation. Besides the lobbying, campaign donations, and market stranglehold that pharmaceutical companies throw at politicians, I see no reason why this can't be changed with relative ease.

Quote:
Quote:
I'd be wary of mandating public research by private firms. A better solution might be to impose production tariffs on pharmaceutical manufacturing, then grant the money to some form of public research organization(s).


Indeed. But at least it shows that solutions exist.

I just think market-only mechanisms are fine when the product is not an absolute necessity. Like video-games. Or portable music players. But with drugs, there is an inherent contradiction. No company will invest in R&D for a drug against a disease that affects poor people. They won't be able to afford it, so the costs won't be recouped.

It's a bit the same as with the medical insurance system you have in the US. Those that need it the most usually can't afford it, and it's a vicous cycle.

Profiteering is definitely a part of the problem, but mandating private research isn't the solution. First, force drug companies to divulge all research on their products. It doesn't make any sense that they should be able to withhold data that may or may not prove effectiveness.

Second, instead of mandating private research, give firms incentive to do it on their own, much like the US is subsidizing ethanol production (although there are unexpected externalities involved with that). Why not divert some tax dollars to subsidize research into "poor" diseases? They could even take the tax money from capital gains and call it an "equity redistribution" or some such.

Edited, Feb 27th 2008 1:35pm by Demea
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#31 Feb 27 2008 at 12:24 PM Rating: Good
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Nobby wrote:
fhrugby the Wise wrote:
I find good sex to be a great anti-depressant.
Smiley: nod

No clue if bad sex works too - I'll cross that bridge if I ever come to it Smiley: grin


I'll check with DF and see if she crossed that bridge.
#32 Feb 27 2008 at 1:06 PM Rating: Good
Overlord Demea wrote:
This is easily solved by a change in legislation. Besides the lobbying, campaign donations, and market stranglehold that pharmaceutical companies throw at politicians, I see no reason why this can't be changed with relative ease.


Indeed. It might happen soonish in the UK, the media are making a bit of a fuss over the whole antidepressant/research hiding hoopla. But I'm not holding my breath.

Quote:
Second, instead of mandating private research, give firms incentive to do it on their own, much like the US is subsidizing ethanol production (although there are unexpected externalities involved with that). Why not divert some tax dollars to subsidize research into "poor" diseases? They could even take the tax money from capital gains and call it an "equity redistribution" or some such.


I agree incentives would be great, if you can make it work within the market its even better. It's all a bit complicated by the fact that these companies are multinational, and that "poor" diseases affect mostly people in the third world. Though none of this is hugely problemtic, and it would be totally doable if there was the political will for it. It's quite obvious that the main problem is that poor and sick third world people don't hire very good lobbysits.
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#33 Feb 27 2008 at 1:08 PM Rating: Excellent
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Though none of this is hugely problemtic, and it would be totally doable if there was the political will for it. It's quite obvious that the main problem is that poor and sick third world people don't hire very good lobbysits.


Nor do people with obscure or rare diseases. Shameful lack of foresight.
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#34 Feb 27 2008 at 1:25 PM Rating: Excellent
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Besides the lobbying, campaign donations, and market stranglehold that pharmaceutical companies throw at politicians, I see no reason why this can't be changed with relative ease.


Besides gravity, I see no reason why I can't fly around by flapping may arms.

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#35 Feb 27 2008 at 1:32 PM Rating: Good
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#36 Feb 27 2008 at 1:35 PM Rating: Good
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Treatment of straight-up clinical depression, most often that not, can be rectified through therapy alone.


Bullsh*t. This has never, ever, been the case. People with "straight up clinical depression" don't exist. I can only assume you mean Major Depressive Disorder, which in most cases, cannot be "rectified" with talk therapy. Studies show talk therapy to have the same efficacy as placebo for treating it, while other therapies do better.

Stop offering your credentials as welfare case worker or whatever completely unrelated job you do as a substitute for having any idea what you're talking about.



Edited, Feb 27th 2008 4:36pm by Smasharoo
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To make a long story short, I don't take any responsibility for anything I post here. It's not news, it's not truth, it's not serious. It's parody. It's satire. It's bitter. It's angsty. Your mother's a *****. You like to jack off dogs. That's right, you heard me. You like to grab that dog by the bone and rub it like a ski pole. Your dad? Gay. Your priest? Straight. **** off and let me post. It's not true, it's all in good fun. Now go away.

#37 Feb 27 2008 at 2:37 PM Rating: Decent
In college I was depressed. In graduate school, I was not. No idea why. I was about 22 years old when the transition occured, and I have not been depressed since. I was never diagnosed, nor treated. So I'm using "depressed" as a colloquism, not whatever the "medical" definition is. Maybe I outgrew it. I was much harder working and spent more time working while depressed. I'm definately a nicer guy now then I was then, and that counts for something.

I'm not going to criticize the drug companies again, the poor bastards, I wouldn't take their place for all the tea in China.
#38 Feb 27 2008 at 2:40 PM Rating: Good
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RedPhoenixxx wrote:
I agree incentives would be great, if you can make it work within the market its even better.

Full disclosure of private testing results should help quite a bit on its own, provided that they currently hide a significant amount of information. Once the research goes public, you can be sure that civil action groups and media entities will dive right in to expose all the dirty little secrets, which will force firms to become more accountable lest they lose (more) credibility with the public.
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#39 Feb 27 2008 at 2:44 PM Rating: Good
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So I'm using "depressed" as a colloquism, not whatever the "medical" definition is.


Which is much of the problem, really. Everyone gets "depressed" from time to time. The drugs are made to treat the sort of crushing reasonless depression that some people, including myself, have suffered from where you wake up absolutely convinced that everything will go wrong, everyone in the world is lying to you, you're a completely worthless person, and everything takes an enormus amount of effort to fight through the overwhelming urge alternately smash things and cry all day for no particular reason.

That's the real problem, it's not depression that's caused by something, it's broken brain chemistry that triggers feelings that should be tied to something, but aren't. No amount of talk therapy is going to fix a chemical problem in your brain any more than talk therapy will cure cancer.

Anyway, it's not something I'm often inclined to talk about, but trust me, it's completely distinct from normal agnsty enui of young adulthood or being sad because of some sort of rational reason, your dog died or you haven't accomplished as much as you wanted to by age 30 or whatever.

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To make a long story short, I don't take any responsibility for anything I post here. It's not news, it's not truth, it's not serious. It's parody. It's satire. It's bitter. It's angsty. Your mother's a *****. You like to jack off dogs. That's right, you heard me. You like to grab that dog by the bone and rub it like a ski pole. Your dad? Gay. Your priest? Straight. **** off and let me post. It's not true, it's all in good fun. Now go away.

#40 Feb 27 2008 at 3:18 PM Rating: Good
Smasharoo wrote:

Treatment of straight-up clinical depression, most often that not, can be rectified through therapy alone.


Bullsh*t. This has never, ever, been the case. People with "straight up clinical depression" don't exist. I can only assume you mean Major Depressive Disorder, which in most cases, cannot be "rectified" with talk therapy. Studies show talk therapy to have the same efficacy as placebo for treating it, while other therapies do better.

Stop offering your credentials as welfare case worker or whatever completely unrelated job you do as a substitute for having any idea what you're talking about.



Edited, Feb 27th 2008 4:36pm by Smasharoo


Wow, okay. Where to start.

First of all, I am employed in an outpatient mental health clinic, providing counseling and case management for individuals with both mental health and substance abuse problems. That's my job description; I do this 40+ hours a week. So, nice assumption about me, but it didn't work.

There are many kinds of depression, and any foray into the DSM or ICD manual will tell you this. In the case of true Major Depressive Disorder, of which there are several subsets, you're right, talk therapy will not necessarily be the only effective course of treatment if it is a recurrent issue for that person. However, that is rare compared to individuals who are depressed more due to life stressors or negative events. This is called Major Depressive Episodes, of which an individual usually must experience two or more of to qualify for Major Depressive Disorder. Just to state pure numbers, it is estimated (although oftentimes depression is misdiagnosed) that about 20% of women and 10% of men will suffer a major depressive episode. That's a fairly significant, but believable number. Now, compare that to ~5% of women and between ~2% of men who are diagnosed with Major Depressive Disorder- quite a difference between those who suffer from an episode of depression, and those who have it as a recurrent problem.

Major Depressive Episode also occurs much more frequently than MDD, from my experience; and although medication can help, it's not the only course of treatment, as this is not necessarily a chronic condition that warrants it...oftentimes simply discussing the underlying issue causing the episode (loss of job, family troubles, it can be a multitude of things) can assist the individual in coming to terms with what was bothering them, and help them to facilitate change within themselves. There are individuals I and others have seen who are able to overcome this type of depression from therapy and group therapy alone- and it's not just "talking about stuff". Cognitive-Behavioral and Motivational Enhancement Therapy, two very effective models of which I ascribe to, places the client in the driver's seat to decide what they want to...it's a very effective and empowering method for many people to help take control of their lives. When a counselor helps a client to feel as if despite what happens to them, they are still in control of how they react, how they behave, and whether or not they wish to change their behaviors- it's very, very helpful. I have seen it happen over, and over and over again. Research has shown that this can be just as effective as medication, even for severely depressed (i.e. MDD recurrent individuals).

Yes, some people whose depression is more severe will need to have medication in conjunction, some will not. However, as an example: if a woman goes to her doctor stating she's depressed because her husband lost his job, they're fighting, or maybe he is now having an affair and she's feeling worthless...in other words meeting all of the diagnostic criteria for a Major Depressive Episode...no, the correct course of action isn't to have her fill a Zoloft prescription on the spot per se; perhaps the answer is she simply needs to sort out the issue with a third party, especially if she does not have a history of depression.

However, my point, which was entirely misconstrued, was that there's this perception that a Major Depressive Episode= full-blown Major Depressive Disorder, and this is wrong. Most of the time, it's people reacting naturally to negative events in their lives.
#41 Feb 27 2008 at 3:21 PM Rating: Good
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I am not a clinician or qualified Social Care Practitioner
Me neither
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#42 Feb 27 2008 at 3:23 PM Rating: Decent
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Wow, okay. Where to start.

First of all, I am employed in an outpatient mental health clinic, providing counseling and case management for individuals with both mental health and substance abuse problems. That's my job description; I do this 40+ hours a week. So, nice assumption about me, but it didn't work.


True, you're likely even less qualified than I'd have thought.




Research has shown that this can be just as effective as medication, even for severely depressed (i.e. MDD recurrent individuals).


Really? Cite some. I won't hold my breath.



Edited, Feb 27th 2008 6:23pm by Smasharoo
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To make a long story short, I don't take any responsibility for anything I post here. It's not news, it's not truth, it's not serious. It's parody. It's satire. It's bitter. It's angsty. Your mother's a *****. You like to jack off dogs. That's right, you heard me. You like to grab that dog by the bone and rub it like a ski pole. Your dad? Gay. Your priest? Straight. **** off and let me post. It's not true, it's all in good fun. Now go away.

#43 Feb 27 2008 at 3:30 PM Rating: Good
Hmm, an MSW degree usually means you're fairly qualified, but okay. Admittedly I am not licensed but that takes supervision time after graduation (working on that now). I'll bite on the research later, I'm at work and on my way out to finish up my evening in an inpatient program. I will be more than happy to provide later tonight, however.
#44 Feb 27 2008 at 3:33 PM Rating: Decent
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Queen Alixana wrote:
I'm at work
No.

You're fUcking about on an message board.

If you were at work you'd be fighting off Mentals and curing them with your management theory
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#45 Feb 27 2008 at 3:35 PM Rating: Good
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Queen Alixana wrote:
Hmm, an MSW degree usually means you're fairly qualified, but okay. Admittedly I am not licensed but that takes supervision time after graduation (working on that now). I'll bite on the research later, I'm at work and on my way out to finish up my evening in an inpatient program. I will be more than happy to provide later tonight, however.


Don't justify yourself. Don't feel the burden of offering research. Smasharoo hasn't exactly offered any qualifications for his point of view. He's speaking out of his *** because if he wasn't he would be able to qualify his statement--basically Cognitive Behavior Therapy is very effective in treatment a Major Depressive Episode but not so much if someone has Major Depressive Disorder or even to an extent, Dysthymia, which is what the medication was designed to treat in the first place. There is a difference between an acute episode and a more chronic problem.

Talk therapy does help people with major depression but only if they are also using medication, in my experience.

Edited, Feb 27th 2008 6:38pm by Annabella
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#46 Feb 27 2008 at 3:36 PM Rating: Good
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Queen Alixana wrote:
Smasharoo wrote:

Treatment of straight-up clinical depression, most often that not, can be rectified through therapy alone.


Bullsh*t. This has never, ever, been the case. People with "straight up clinical depression" don't exist. I can only assume you mean Major Depressive Disorder, which in most cases, cannot be "rectified" with talk therapy. Studies show talk therapy to have the same efficacy as placebo for treating it, while other therapies do better.

Stop offering your credentials as welfare case worker or whatever completely unrelated job you do as a substitute for having any idea what you're talking about.



Edited, Feb 27th 2008 4:36pm by Smasharoo


Wow, okay. Where to start.

First of all, I am employed in an outpatient mental health clinic, providing counseling and case management for individuals with both mental health and substance abuse problems. That's my job description; I do this 40+ hours a week. So, nice assumption about me, but it didn't work.

There are many kinds of depression, and any foray into the DSM or ICD manual will tell you this. In the case of true Major Depressive Disorder, of which there are several subsets, you're right, talk therapy will not necessarily be the only effective course of treatment if it is a recurrent issue for that person. However, that is rare compared to individuals who are depressed more due to life stressors or negative events. This is called Major Depressive Episodes, of which an individual usually must experience two or more of to qualify for Major Depressive Disorder. Just to state pure numbers, it is estimated (although oftentimes depression is misdiagnosed) that about 20% of women and 10% of men will suffer a major depressive episode. That's a fairly significant, but believable number. Now, compare that to ~5% of women and between ~2% of men who are diagnosed with Major Depressive Disorder- quite a difference between those who suffer from an episode of depression, and those who have it as a recurrent problem.

Major Depressive Episode also occurs much more frequently than MDD, from my experience; and although medication can help, it's not the only course of treatment, as this is not necessarily a chronic condition that warrants it...oftentimes simply discussing the underlying issue causing the episode (loss of job, family troubles, it can be a multitude of things) can assist the individual in coming to terms with what was bothering them, and help them to facilitate change within themselves. There are individuals I and others have seen who are able to overcome this type of depression from therapy and group therapy alone- and it's not just "talking about stuff". Cognitive-Behavioral and Motivational Enhancement Therapy, two very effective models of which I ascribe to, places the client in the driver's seat to decide what they want to...it's a very effective and empowering method for many people to help take control of their lives. When a counselor helps a client to feel as if despite what happens to them, they are still in control of how they react, how they behave, and whether or not they wish to change their behaviors- it's very, very helpful. I have seen it happen over, and over and over again. Research has shown that this can be just as effective as medication, even for severely depressed (i.e. MDD recurrent individuals).

Yes, some people whose depression is more severe will need to have medication in conjunction, some will not. However, as an example: if a woman goes to her doctor stating she's depressed because her husband lost his job, they're fighting, or maybe he is now having an affair and she's feeling worthless...in other words meeting all of the diagnostic criteria for a Major Depressive Episode...no, the correct course of action isn't to have her fill a Zoloft prescription on the spot per se; perhaps the answer is she simply needs to sort out the issue with a third party, especially if she does not have a history of depression.

However, my point, which was entirely misconstrued, was that there's this perception that a Major Depressive Episode= full-blown Major Depressive Disorder, and this is wrong. Most of the time, it's people reacting naturally to negative events in their lives.

I never thought that somebody would come to these forums that could out-gbaji gbaji.

Congrats?

And, just like his posts, I'll now start to automatically skip over yours and read the relevant parts in other peoples' replies.

Edited, Feb 27th 2008 5:37pm by Demea
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#47 Feb 27 2008 at 3:40 PM Rating: Good
It's 6:30pm and I was doing paperwork after a group. I had time to "f*ck around on a message board" before my 7pm appointment. I like your idea though, maybe I will do all of that tomorrow, Nobby.

Off I go! Thanks for your support, Annabella. Not that I mind someone opposing my viewpoints, but lately I'm feeling that I'm being shot down because some have simply taken a dislike to me. I prefer to discuss things maturely, but if I am going to have to justify myself at every turn, I'll just find somewhere else to share my thoughts. Have fun! :)
#48 Feb 27 2008 at 3:42 PM Rating: Decent
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Hmm, an MSW degree usually means you're fairly qualified, but okay.


To asses the efficacy of drug therapy vs talk therapy in treating depression? Are you stealing crack from your patients?

A MSW degree usually means you're fairly qualified to do ******* SOCIAL WORK, which is a fine and noble endeavor in and of itself, but which has absolutely nothing to do with psychopharmacology. You're probably qualified to comment on behavioural development or systems theory or family family counseling, or in your case certainly the effectiveness of various rehabilitation programs, but when it comes to the efficacy of drug vs talk therapy for the clinical treatment of depression you're about as qualified as an elephant trainer. Although in fairness, the elephant trainer likely wouldn't assume he could make unfounded proclamations based on his unrelated job experience.
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#49 Feb 27 2008 at 3:46 PM Rating: Decent
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Talk therapy does help people with major depression but only if they are also using medication, in my experience.


Scrambled eggs help them too, but only if they are also using medication.

I hate to break it to you, girls, but there's a very very good reason social workers can't prescribe medication.


Smasharoo hasn't exactly offered any qualifications for his point of view. He's speaking out of his *** because if he wasn't he would be able to qualify his statement--basically Cognitive Behavior Therapy is very effective in treatment a Major Depressive Episode but not so much if someone has Major Depressive Disorder or even to an extent, Dysthymia, which is what the medication was designed to treat in the first place.


That wasn't my statement, kitten. My statement was in response to this:


Research has shown that this can be JUST AS EFFECTIVE as medication, even for severely depressed (i.e. MDD recurrent individuals).


That's what you're defending, by stating the opposite. Good work.

You and I both know it's not JUST AS EFFECTIVE, and that no reputable peer reviewed studies exist saying so.

Go back to your passive aggressive defensive dismissals though. It gives credit to your profession.



Edited, Feb 27th 2008 6:48pm by Smasharoo
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To make a long story short, I don't take any responsibility for anything I post here. It's not news, it's not truth, it's not serious. It's parody. It's satire. It's bitter. It's angsty. Your mother's a *****. You like to jack off dogs. That's right, you heard me. You like to grab that dog by the bone and rub it like a ski pole. Your dad? Gay. Your priest? Straight. **** off and let me post. It's not true, it's all in good fun. Now go away.

#50 Feb 27 2008 at 3:47 PM Rating: Good
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Smasharoo wrote:

Hmm, an MSW degree usually means you're fairly qualified, but okay.


To asses the efficacy of drug therapy vs talk therapy in treating depression? Are you stealing crack from your patients?

A MSW degree usually means you're fairly qualified to do @#%^ing SOCIAL WORK, which is a fine and noble endeavor in and of itself, but which has absolutely nothing to do with psychopharmacology. You're probably qualified to comment on behavioural development or systems theory or family family counseling, or in your case certainly the effectiveness of various rehabilitation programs, but when it comes to the efficacy of drug vs talk therapy for the clinical treatment of depression you're about as qualified as an elephant trainer. Although in fairness, the elephant trainer likely wouldn't assume he could make unfounded proclamations based on his unrelated job experience.


Do you know how unqualified psychiatrists are to talk about talk therapy? Trust me, they receive very little training and have very little experience. That's why most people work on teams. Chances are she works on interdisciplinary teams where she is one of the players who make decisions about treatment efficacy. To be effective in her role, she has to be knowledgeable about making that distinction. You might not agree with her POV but to maintain that she has no ability to form an educated opinion on one, especially in comparison with the rest of the board, is ridiculous.

Quote:

That's what you're defending, by stating the opposite. Good work.


I do tend to read about 20% of most posts over a paragraph. lol. Sorry.

Edited, Feb 27th 2008 6:48pm by Annabella
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#51 Feb 27 2008 at 3:50 PM Rating: Decent
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Do you know how unqualified psychiatrists are to talk about talk therapy? Trust me, they receive very little training and have very little experience. That's why most people work on teams. Chances are she works on interdisciplinary teams where she is one of the players who make decisions about treatment efficacy. To be effective in her role, she has to be knowledgeable about making that distinction. You might not agree with her POV but to maintain that she has no ability to form an educated opinion on one, especially in comparison with the rest of the board, is ridiculous.


I'm not comparing her to the rest of the board.
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To make a long story short, I don't take any responsibility for anything I post here. It's not news, it's not truth, it's not serious. It's parody. It's satire. It's bitter. It's angsty. Your mother's a *****. You like to jack off dogs. That's right, you heard me. You like to grab that dog by the bone and rub it like a ski pole. Your dad? Gay. Your priest? Straight. **** off and let me post. It's not true, it's all in good fun. Now go away.

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