I love having spiders around the house to keep the insects down. If you remove webs from around the house you get left with the spiders that dont' spin webs. I never owned insect spray, but I will draw the line at a spider that can kill a human living in a heavily trafficked area.
A red-back spider moved into my VCR a few years ago and I bought a can of insecticide just for it. I wasn't going to try the glass-jar, piece of paper, catch and release in the garden trick on a spider that would require an ambulance ride if I got bitten.
Average number of insects a human eats in their sleep a year: 5.