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#77 Jan 17 2007 at 9:15 PM Rating: Good
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paulsol the Flatulent wrote:
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Actually, to be more accurate, you didn't even bother with the conclusion either (but one was implied: We're wasting money on the war that could be spent on stem cell research instead").


Not my implication at all in fact.

I think that the money would be better spent on anything other than bombing and killing people who were no threat to you.


Really!?

paulsol the Flatulent wrote:
I was merely making a facetious comment on the relative costs of the federal funding of the costs of bombing a bunch of foreigners (who never, ever, EVER had the means to attack you ) into half a million early graves, and the comparitivly trivial sum of 39 million bucks, wich may, or may not, lead to some sort of cure for people with diseases.


Odd. You didn't say "The cost of attacking Iraq was a waste of money". You specifically talked about the "relative cost" of spending that money on Iraq compared to the "trivial sum" spent on ESC research...


I'm sorry. What was the point of making that comparison again? What's funny is that all you've really done here is highlight the "arguing without making an argument" point I was just making. You made the statement, knowing full well that the *only* intepretation of that statement is that money that could be spent on stem cell research is being spent instead of the war in Iraq, and knowing full well that every single person who reads your statement will interpret your statement in that exact way. But then, when called on it, you have the luxury of backing away and saying "Wait a minute! I didn't say that!!!".

Been there. Seen this a million times. Got the t-shirt. I'll say again: How about, if you have an argument to make, you actually make it instead of kinda nibbling about the edges and trusting that everyone will "get" what you mean without you actually having to go out on a limb and say it yourself?

I find that style of debate tedious and cheap (as I stated earlier). Have the cajones to actually state what you believe and be willing and able to back it up logically. I don't think it's that much to ask...
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#78 Jan 17 2007 at 9:36 PM Rating: Good
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Jophiel wrote:
gbaji wrote:
Except that you are in essense arguing that since a scientist said that his research should not result in a shift or change in funding to some other area that we should take that as a solid reason to continue funding that other area.
Well, when politicans are attempting to use hs study as a basis to prevent that funding then, yeah, I'd say the opinion and analysis of the guy who wrote the study is pretty critical. Much moreso than that of a random Congresscritter who probably couldn't pass a Biology 101 test but suddenly declares the study as "solid scientific backing" to promote his cause.


Except that they're not using it to "prevent funding". They're using it to block a change to law that would fund an ethically questionable proceedure related to the research. See how "not increasing funding into a new area" is not the same as "removing funding on existing research"?

Bush's veto does not reduce funding to ESC. It prevents that funding from flowing into areas that were not previously funded.

When you can quote the scientist in question saying that his research means that we should expand funding for ESC into funding the harvesting of human embryos *then* you might have a point.


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Bush's veto now has much more solid scientific backing and was the right thing to do IMO.
Except that, absent any scientific consensus that embryonic research is unnecessary, it doesn't.


A) No one said that "embryonic research" was unecessary. Only that lifting the ban on federal funding of new embryos was. Bush's veto only does the latter, so how about you limit your condemnation of it to that one funding issue?

B) As I've pointed out time and again. You'll have almost no success *ever* finding a scientific consensus that state that *any* form of research is unecessary.

C) The data from the research itself states that amniotic stem cells are pluripotent. It's the pluripotent aspect of ESC that was the *only* reason anyone could even begin to justify harvesting human embryos for that line of research. Thus, Bush's veto has "more solid scientific backing" with this new research then it did before. I'm not sure how you can even debate this issue. Last veto, there was nothing more then some promising research that there might be a discovery of methods to obtain pluripotent stem cells without having to destroy embryos to get them. Now we have direct research providing a method of doing this. How is does that not provide more scientific backing for the veto?


Scientists don't generally say "There's no need to fund research for this". They just don't. It's up to exactly those politicians and their advisors to decide what gets funded and how much. We don't elect the scientists. We elect the people who fund them in this case. They get to make that decision. Yeah. I know. Silly of them to use ethics when making that decision.

At the risk of invoking Godwin's, I'm going to make a comparison to **** style human experiementation and how they led to discoveries about the human body that are still used by medical professionals today. We could argue that they were "necessary". They certainly advanced our knowledge of the human body significantly. But I doubt strongly that you'd argue they were ethical, or that their necessity outweighed the ethical problems. The mere fact that research bears fruit is not the *only* consideration used here. I'm not trying to imply that those arguing for this funding are ***** or anything, but merely pointing out that it's not a bad thing to balance the usefulness of an area of research with the ethics of the research. And to be honest, I'd rather we have leaders who are "ethically cautious" then the other way around...
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#79 Jan 17 2007 at 10:19 PM Rating: Excellent
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gbaji wrote:
When you can quote the scientist in question saying that his research means that we should expand funding for ESC into funding the harvesting of human embryos *then* you might have a point.
Smiley: laugh

What? You are trying to use his study as a basis to justify Bush's veto. Dr. Atala has said "Some may be interpreting my research as a substitute for the need to pursue other forms of regenerative medicine therapies, such as those involving embryonic stem cells. I disagree with that assertion [...] [It is] essential that National Institutes of Health-funded researchers are able to fully pursue embryonic stem cell research as a complement to research into other forms of stem cells."

In other words, Atala's study doesn't mean what you're trying to say it means. It is not, per Dr. Atala, a justification for vetoing the law. The opinion of you, or Bush or whatever Congresscritter who says otherwise is much, much less relevant than the analysis of the guy who wrote the friggin' study in the first place. But, I know, I know... there's no reason to believe that Dr. Atala is giving his professional opinion. The only possible explanation is because all the other scientists would be mad at him if he dared tell the truth.
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No one said that "embryonic research" was unecessary. Only that lifting the ban on federal funding of new embryos was.
Gbaji previously wrote:
...given that there is absolutely zero scientific evidence that the usefulness of embrionic stem cells is any greater then that of amniotic stem cells.
Uh huh, then.
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As I've pointed out time and again. You'll have almost no success *ever* finding a scientific consensus that state that *any* form of research is unecessary.
And, as I asked you several times, find me one person. One. Let's start with that. Find me one person who has the same qualifications as these others who can say that it's unnecessary.

Oh, that's right... they can't because of peer pressure and funding and yadda yadda let me make up some more random bullshit to hide my complete lack of sources. Smiley: rolleyes
Quote:
C) The data from the research itself states that amniotic stem cells are pluripotent. It's the pluripotent aspect of ESC that was the *only* reason anyone could even begin to justify harvesting human embryos for that line of research.
Scientific American wrote:
Atala says that compared with other types of pluripotent stem cells--save embryonic stem cells--AFS cells are "truly pluripotent" and that their major advantage is that after two weeks of culturing they expand quickly, doubling every 36 hours so that they are in large supply.
The analysis from Dr. Atala himself states that much, much more research has yet to be done to determine the exact usefulness of these cells. Dr. Atala excludes embryonic stem cells from his list of pluripotent cells that amniotic cells compare to. Again, have you read the study or are you parroting what you read from other sources?

It's funny how I can find a half dozen scientists in the field speaking about why these cells are not necessarily a substitution and the best you can come up with are tortured rationalizations about "How come he said embryonic here? Huh???" but I'm supposed to give a rat's *** about your analysis of a study you know only from news sources.

"Hey! I read something in CNS News saying that these cells are pluripotent! That's all I understand from a six page paper I've never read but it's enough for me to second guess any scientist who has reservations and accuse them of distorting the facts!"

As for your pathetic attempt to link embryonic research with **** studies, you need to first build a case as to why research on donated embryos is unethical. Personally, my opinion is that incinerating embryos that could be potentially saving lives (with the consent of the parents) because the funding to use them has been vetoed by Bush is unethical.
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#80 Jan 17 2007 at 11:08 PM Rating: Good
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Jophiel wrote:
gbaji wrote:
When you can quote the scientist in question saying that his research means that we should expand funding for ESC into funding the harvesting of human embryos *then* you might have a point.
Smiley: laugh

What? You are trying to use his study as a basis to justify Bush's veto. Dr. Atala has said "Some may be interpreting my research as a substitute for the need to pursue other forms of regenerative medicine therapies, such as those involving embryonic stem cells. I disagree with that assertion [...] [It is] essential that National Institutes of Health-funded researchers are able to fully pursue embryonic stem cell research as a complement to research into other forms of stem cells."


He does not say that we should expand federal funding into the harvesting of more embryos for research. Thus, you cannot interpret his statement to have that meaning. You can only say that he's stating that his research should not be used as an excuse to "stop or reduce" funding (the "substitute" word is key here, since in terms of funding it means replacing funds for ESC with funds for AFS).

Reading more into it then that is you putting your own opinion into the issue. He did not say that Congress should lift the ban, nor did he comment on Bush's veto of the attempt to do so. You are *guessing* that he meant that, but you have to add significantly to his statement to arrive at that conclusion.

Quote:
In other words, Atala's study doesn't mean what you're trying to say it means. It is not, per Dr. Atala, a justification for vetoing the law.


It's not a refutation of the veto of the law either. He simply does not state a position on it one way or the other. You're trying really hard to twist his words to make it seem like he is though.


Quote:
Quote:
C) The data from the research itself states that amniotic stem cells are pluripotent. It's the pluripotent aspect of ESC that was the *only* reason anyone could even begin to justify harvesting human embryos for that line of research.
Scientific American wrote:
Atala says that compared with other types of pluripotent stem cells--save embryonic stem cells--AFS cells are "truly pluripotent" and that their major advantage is that after two weeks of culturing they expand quickly, doubling every 36 hours so that they are in large supply.
The analysis from Dr. Atala himself states that much, much more research has yet to be done to determine the exact usefulness of these cells. Dr. Atala excludes embryonic stem cells from his list of pluripotent cells that amniotic cells compare to. Again, have you read the study or are you parroting what you read from other sources?


Um. Joph? Re-read that quote. You're reading it wrong.

It says "... compared with other types of pluripotent stem cells--save embryonic stem cells--AFS cells are "truly pluripotent""

He's saying that compared to all cells other then embryonic cells, AFS cells are "truely pluripotent". In otherwords, other stem cells are not pluripotent (or "truely pluripotent" as he calls it), ESC *and* AFS cells *are* truely pluripotent.

The problem is one of semantics. He used the incorrect word. He should have said "contrasted", rather then "compared". A common mistake in the English language. He is "contrasting" the properties of AFS cells and all other stem cells *except* embryonic cells. AFS cells differ from those other types in that they are truely pluripotent. Embryonic cells *also* differ from those other types in that they are truely pluripotent. Thus, both AFS and ESC are similarly unique in that they are both truely pluripotent, while all other stem cells are not.

I'm serious Joph. This isn't a "I'm arguing for the sake of arguing" here. I really think you misread that statement. It's saying the exact opposite of what you think it says, which may explain quite a bit of your argument.

It's confusing because he's essentially using a double negative form in his sentence. He's showing the differences between AFS and other stem cells *except* ESC. Thus, he's actually saying that AFS and ESC share that difference. ESC is the "exception" in that it also is truely pluripotent. Your interpretion of the statement makes no sense if you stop and think about it, because you'd be saying that all other pluripotent cells are "truely pluripotent" (like AFS cells), but somehow ESC are different in that they are *not* truely pluripotent". That makes zero sense. He's saying that only AFS and ESC are truely pluripotent, while all other cells are not. Read it again slowly and carefully. It does not say what you think it does.
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#81 Jan 17 2007 at 11:21 PM Rating: Excellent
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gbaji wrote:
He does not say that we should expand federal funding into the harvesting of more embryos for research.
gbaji wrote:
He did not say that Congress should lift the ban
Yes, he did. I'm sorry that you know so little about this and can only go off of what I had quoted but Dr. Atala concluded his letter with:
Dr. Atala wrote:
Your legislation, the Stem Cell Research Enhancement Act of 2007, H.R. 3, would update the current federal embryonic stem cell policy and allow federally funded researchers to conduct research on an expanded set of embryonic stem cells within an ethical framework. I believe this legislation would speed science in the regenerative medicine field, and I support its passage.
But I guess that was just me, trying to twist his words, huh? Smiley: rolleyes

Edited, Jan 17th 2007 11:18pm by Jophiel
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#82 Jan 17 2007 at 11:29 PM Rating: Good
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Note to Nobby - Please edit post title to "Gbaji pwnt"

ps - rate up Iophiel!
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#83 Jan 18 2007 at 3:55 PM Rating: Good
gbaji wrote:
Ok. Couple issues with this:

They *also* don't know exactly how many different cell types can be made from embryonic stem cell either.


All of them come from embryonic stem cells, by definition.

I could keep quoting your post and point out how the vast majority of your writing belies a total lack of knowledge but I'll stick with:

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And Yossarian? If you had read the various articles on the subject, you'd see that the "big breakthrough" was the research results showing that amniotic stem cells *are* pluripotent (or at least as demonstably pluripotent as any ESC's we've worked with so far).


I, uh, read the Nature article's abstract. Perhaps the newpaper articles have mislead you. I posted a link to the article abstract. Click it. Ya they claim it is multipotent, not pluripotent. They also have a great tendancy not to form turmors. They look great! It's really exciting; that's why it is in Nature.

The one thing I should stress to you about Nature is that they don't print rehashes. This, incidentally, is why so much in the big name journals such as Science and Nature and PNAS later turn out to be wrong - it has to be new and really big news.

1. No one bases scientific knowledge off a single article before others have had a chance to repeat it.

2. Even if everything in the Nature article is true, we know ESC turn into everything, not the few things listed in the article abstract (go read it). Research on them is still warrented.
#84 Jan 18 2007 at 8:59 PM Rating: Excellent
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yossarian wrote:
Gbaji wrote:
And Yossarian? If you had read the various articles on the subject, you'd see that the "big breakthrough" was the research results showing that amniotic stem cells *are* pluripotent (or at least as demonstably pluripotent as any ESC's we've worked with so far).
I, uh, read the Nature article's abstract. Perhaps the newpaper articles have mislead you. I posted a link to the article abstract. Click it. Ya they claim it is multipotent, not pluripotent.
Nature wrote:
Lines maintained for over 250 population doublings retained long telomeres and a normal karyotype. AFS cells are broadly multipotent. Clonal human lines verified by retroviral marking were induced to differentiate into cell types representing each embryonic germ layer, including cells of adipogenic, osteogenic, myogenic, endothelial, neuronal and hepatic lineages.
Rate ups for Yossarian instead!

Gbaji double pwnt! Smiley: laugh

Did I mention that Gbaji's entire understanding of this came from reading some conservative web news article? No doubt Dr. Atala just screwed up the semantics when he wrote his study and he obviously really meant to say "they're pluripotent". Because Gbaji would know better.

Smiley: laugh

Edited, Jan 18th 2007 8:49pm by Jophiel
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#85 Jan 19 2007 at 6:36 PM Rating: Good
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Jophiel wrote:
Yes, he did. I'm sorry that you know so little about this and can only go off of what I had quoted but Dr. Atala concluded his letter with:
Dr. Atala wrote:
Your legislation, the Stem Cell Research Enhancement Act of 2007, H.R. 3, would update the current federal embryonic stem cell policy and allow federally funded researchers to conduct research on an expanded set of embryonic stem cells within an ethical framework. I believe this legislation would speed science in the regenerative medicine field, and I support its passage.
But I guess that was just me, trying to twist his words, huh?


Why they hell didn't you quote that (or provide a usable link to the letter)? Could have saved us a hell of a lot of time... Sheesh!


I still think that's just a scientist after realizing that his research may put other peer's research funding in jepoardy, writing something to try to protect them. You may disagree, but that's certainly what it looks like to me.

Ultimately, it's not *his* choice to decide what gets funded or not. That's the point here Joph. His opinion as to where the research funds should go, or which bills in Congress should be passed are no more valid then anyone elses. An assessment of the viability of his research may influence funding down the line, but his written opinions directly related to funding do *not*.


And Yossarian? Your quote is irrelevant. The problem is that the terms "multipotent" and "pluripotent" seem to be used slightly differently depending on who's using them. However, typically multipotent just means that the cells can be used for multiple applications within a particular cell type. Pluripotent cells can be programmed to become any of those broad cell types *and* are also multipotent within each of those types.

The two terms are not exclusive. One is a subset of the other, in the same way that a square is also a rectangle. All pluripotent stem cells are *also* multipotent. So the fact that AFS cells are multipotent does not exclude them from being pluripotent. Given that Dr. Atala states clearly that AFS *are* "truely pluripotent", it's somewhat absurd to argue that a Nature article that says they are multipotent somehow means that they aren't pluripotent.


Again. His science and his opinion on the funding ramifications of his science should be treated as two separate things. I'll point out again that you'll be hard pressed to *ever* find a scientist who'll claim that funding for science of any particular type isn't needed (even something he's not working on himself). The fact that he supports any given form of funding does not mean that we *should* be providing that funding.
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#86 Jan 19 2007 at 7:12 PM Rating: Excellent
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Look, I'm not going to keep arguing this with you when you're so obviously uneducated about it beyond some news articles and your own steadfast conviction that you know better about it than Dr. Atala.

Suffice to say, you're wrong. Go do some research on it, go read his interviews and the articles that go deeper than CNS and see how he defines the spectrum of cells and where amniotic ones lie and why he would use the terms he uses rather than trying to lecture us all on semantics. Because you're the only one who doesn't get it.
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#87 Jan 19 2007 at 7:15 PM Rating: Decent
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Because you're the only one who doesn't get it.


As usual.
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#88 Jan 19 2007 at 8:15 PM Rating: Good
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Sure. I don't "get" it. What exactly do I not get?

I "get" that amniotic stem cells show the exact same features that make embryonic stem cells important.

I "get" that amniotic stem cells are cheaper to harvest, more abundant, and do not require an ethically questionable harvesting process to obtain.

I "get" that embryonic stem cells are more expensive to harvest, less abundant, and *do* have significant ethical baggage regarding the harvesting process.

Is there really a need to "get" more then that? Those facts are sufficient IMO to oppose federal funding for the harvesting of additional lines of embryonic stem cells. Until it can be shown that only be opening up additional lines of ESC can we obtain needed treatments that no other form of stem cell can give us, I'm not going to change my position on this.

So far, nothing anyone has said, written, or researched has meet that criteria. I really don't even understand why this is such a huge debate. It should be *obvious* to everyone that it makes more sense to avoid the ethically challenged methods of science if there are "better" ways of doing the same thing.


Silly me. I think that pursuing science in an ethical manner is pretty darn important. We should be willing to pay more and take more time to do things in a more ethical manner. It frankly suprises me that so many people seem unable to grasp this in this particular case (and seemingly *only* in this case). As I've pointed out before, if this were any other scientific field and there were two paths to pursue, most of you would insist we follow the ethically cleaner one no matter what the relative cost.

Apparently though, Liberals only hold those high values when it's politically convenient for them to do so. At least that's the only reason I can think of why there's so much debate over this.
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#89 Jan 19 2007 at 9:02 PM Rating: Good
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You don't get the word 'get', gbaji.
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#90 Jan 19 2007 at 9:03 PM Rating: Excellent
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gbaji wrote:
Sure. I don't "get" it. What exactly do I not get?
Exactly.
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#91 Jan 20 2007 at 12:23 AM Rating: Good
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He won't even address the fact that he consistently and blatantly lied about ethics being the issue.


It's because he exists in his own little bubble. Just like how he argues reasons supporting the Iraq war that for some reason, even the president and his press secretary don't mention. You'd think if they were such compelling arguments, that the white house would be making them.


#92 Jan 21 2007 at 6:58 AM Rating: Excellent
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trickybeck wrote:
He won't even address the fact that he consistently and blatantly lied about ethics being the issue.
Dude, that was just semantics!

Of course it's about "ethics". The funny thing about his ham-handed attempt to take some moral high ground is that it still hasn't been explained why research on a voluntarily donated "excess" embryo which might potentially save lives upon lives is less "ethical" than tossing that embryo into the flames. Or keeping it on ice until its no longer viable and has to be destroyed. Or until the parents can no longer afford to keep the child frozen and it has to be destroyed. Out of all those options, voluntary research seems, to me, to be the most ethical.

I'm not the first one to have this revelation, but I honestly believe that this isn't about embryonic research. It's about abortion. Some people on the Right are so terrified to give any ground and weaked their anti-abortion stance that they'd rather have embryoes meaninglessly incinerated than admit that there's nothing less ethical about that embryo being used to save lives.

So they'd rather trumpet a program that "saves" less than 0.005% of the stored embryos while thousands of embryos are meaninglessly destroyed instead of advancing cures and therapies.

Gee, I feel so unethical.
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Belkira wrote:
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