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WASHINGTON - Chronic heartburn appears to be fueling the nation's fastest-growing cancer, esophageal cancer. Some 3 million Americans are thought to have a type of esophagus damage from severe acid reflux that puts them at increased risk for the deadly cancer — and new research is exploring whether it's possible to zap away that damage and block the cancer from ever forming.
This is the first I've heard of this, and I'm surprised. Of course it's not implying direct causation but rather a heightened risk, but it's still pretty sobering, considering that, according to the article,
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About 14,550 Americans will be diagnosed with esophageal cancer this year, the American Cancer Society estimates. Most won't be diagnosed until they feel such symptoms as trouble swallowing and loss of appetite. The prognosis is grim: Just 16 percent of esophageal cancer patients survive five years, and 13,770 are predicted to die this year.
Most have esophageal adenocarcinoma, the type linked to severe chronic heartburn.
Most have esophageal adenocarcinoma, the type linked to severe chronic heartburn.
Here's the reasoning in the most bite-sized piece:
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With this "gastroesophageal reflux disease," or GERD, a loose valve allows stomach acid to regularly back up into the delicate esophagus. In a fraction of heartburn sufferers, most over age 50, severe GERD over many years actually changes the lining of the esophagus: When the stomach acid kills cells in that lining, the esophagus eventually starts healing itself with more acid-resistant cells — which happen to be cancer-prone.
It's a condition called Barrett's esophagus, and Barrett's sufferers are thought to be at least 30 times more likely than the average person to get esophageal cancer.
It's a condition called Barrett's esophagus, and Barrett's sufferers are thought to be at least 30 times more likely than the average person to get esophageal cancer.