I'd be a hardcore painkiller addict if it wasn't for respecting my family immensely, and knowing that I'll never really be happy with who I am if I were to get into it. However, many of my friends wonder why I love painkillers so much when they're prescribed to me or when given to help the bad migraines I occasionally get. Turns out, from reading up on hydrocodone and the like, there's a certain enzhyme in the liver that only a certain amount of people have.
For those that have it, it turns the painkiller's effect into a much better experience. Granted, if anyone took x more than the recommended dosage of the higher tier painkillers they'd probably have a good time (assuming they have a full stomach to prevent nausea), but those with the enzyhme will, for the most part, probably get more out of them than someone without.
Now, it's either that or I got my info on dextromethorphan mixed up with painkillers. Or, they both share an enzhyme (where the dextromethorphan's enzhyme helps regulate and keep your trip through the hallucinogen enjoyable.)
I guess you could say there's a good aspect to having friends who are a part of the drug crowd, it's given me a seemingly fun little hobby in studying drugs, their affects, and why they do what they do.
Ode to the sweet, sweet feeling of having more proteins with analgesic properties released in the brain.