I'm really interested to see what they will do after 65 nm.
They'll have to start using FinFETs or trigate transistors, they just can't get much below 65 nm with conventional transistors.
They've already got gate oxides that are only a nanometer in thickness.
So, just from the process point of view, I'm curious to see what will happen.
As far as the architectures go, I'm just waiting for Intel to completely scrap their desktop design and adopt a multi-core architecture based off of the Pentium M.
AMD's architecture is going to scale much better than Intel's on the desktop side, and for desktops, it's going to be all about multiple cores on a single die.
They did away with the marketing frequency hype, so perhaps now they can actually build an architecture without forty pipeline steps just so they can claim the highest operating frequency.