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I've tried the Seed spamming, but I always end up pulling aggro from that one mob the tank doesn't have under control.
I thought I was the only one who had this problem! I have yet to develop a safe, reliable strategy for SoC.
I usually try to Seed a couple of non-priority mobs, then try to get one on the main target before it dies. If you've got someone else doing AoE (mage, hunter, etc.), you can almost guarantee that your SoC will pop within a couple of seconds. Obviously, SoC's safer when you've got an AoE tank like a paladin or Unholy death knight.
Does anyone have any advice for using Seed of Corruption?