As noted above from the EJ quote, it's not really a rotation as much as a flowchart. I tend to think of things in order of priority. HfB > SnD > Rupture. Right now I'm using the SnD, Rupture and Garrote glyphs as majors.
Positioning isn't just about Mutilate not needing it's old requirement, it's about removing Parry from the hit table. Imagine there is an arc of about 180-degrees behind boss mobs. That's the zone to be in more or less. If there is a tail swipe, move out to the edge of the arc. If you start seeing parries, move a bit back into the middle of the arc.
Link to the quoted Elitist Jerks post.
Good luck out there.