I think right now the flavor build is 21/0/50, picking up most of the unholy damage talents, and then the blood defensive talents (such as blade barrier, rune tap, and mark of blood). I like the idea of taking 3 points out of RoR to put into VotTW though. Lose 6% damage on diseased targets, gain 3 expertise, 6% strength, and 6% stamina.
Overall, Unholy or Frost builds are both pretty good, as they offer a bit of control and a bit of burst damage. Blood offers a lot of survivability, which isn't going to keep you from being kited or burst people down when you do get to them. I think frost is a bit more control and unholy is a bit more burst, that's why a lot of people like burst.
I personally am thinking of a 24/47/0 build, which focuses on turning my blood runes into death runes, then keeping them death runes with oblit.