Yeah I forgot about Sonic Boom. If you don't have your poison ticking, your dps drops to zero while you're running. Then again, you could cloak through the boom and stay inside, at least once when Evasion is available.
A somewhat related question there then: Do poison effects applied by others, like a hunter's sting or snake trap, or even poison from another rogue count for the Mutilate bonus damage? The tooltip doesn't specify that it has to be the mutilating rogue poisoning the target, or that it has to be rogue poison at all.