Regem all non-hit gems to +9dmg (and replace the +hit gems as soon as you can, 76 hit rating with 5/5 Shadow Focus is hit cap).
Enchant your helm (revered with Sha'tar), shoulders (honored/exalted Aldor, OR exalted Scryers - the honored Scryers one sucks), and boots (Vitality or Boar's Speed).
Helm - Grab the one off Hex Lord to replace Spellstrike once you get there. With that in mind, you may want to grab Trial-Fire if no one else wants them for after you break the set bonus, or possibly ignore Spellstrike Pants all together *if* you'll the helm quickly.
Neck - The Kara trash one. If you have absolutely abysmally drops on that, go for the PvP one with +9dmg gem.
Cloak - Personally I like the one from Prince (Ruby Drape of the Mysticant) because it trades very little +dmg for extra stats and a hefty chunk of hit. Otherwise, the one from Moroes.
Bracers - Vindicator's Dreadweave, +9dmg gem, +15dmg enchant
Hands - Studious Wraps, 60 Badges, 2 +9dmg gems, +20dmg enchant
Belt - Girdle of Ruination, or for a cheaper alternative, the belt off the last boss in heroic mana-tombs. If you're sitting in cash, get Belt of Blasting made, it's the second-belt belt until Sunwell, but will cost you quite a bit.
Legs - Spellstrike is better than Trial-Fire, though not by a whole lot, and only with the set bonus. Alternatively, get into a PuG Doom Lord Kazzak and get those pants off him, but with the Spellstrike set you're best going after those. Get the Runic Spellthread on whatever you get.
Rings - Grab the one from Heroic Mana-Tombs to replace the Kara one you have now. Then replace the two (identical) ones you have with the ones from ZA.
Trinkets - Icon of the Silver Crescent, Darkmoon Card: Crusade, and eventually Hex Shrunken Head. Grab the cheap PvP one (15 marks) in Zangarmarsh to replace the Vengeance trinket.
Weapon - Merciless or Vengeful Glad's are best. If not, then I'd hold out for the mace or dager from ZA. Get Soulfrost on it.
Offhand - Orb of the Soul-Eater.
Wand - Carved Witch Doctor's Stick (which looks @#%^ing awesome in the next patch!)
Once you hit ZA and 25-mans, be sure to pop a Flask of Pure Death, keep 8 stacks of mana pots on you, a stack of damage food, and a few Superior Wizard Oils as well. I'd also suggest stocking up on gems and enchanting mats and then bringing them with you so that you can gem/enchant new items immediately after getting them.
Edited, Dec 10th 2007 11:58am by lsfreak