OH, there's lots that familiar. The Mage's Tower is in South Qeynos, with some stores I'm sure you'll recognize. Sneed's great great something or other grandson runs the general store in Qeynos North. Antonica is what used to be Qeynos Hills and part of the Karanas, and yes, Blackburrow is there and Holly Windstalker's ghost will be happy to kick your butt for old time's sake!
Thundering Steppes is what's left of the rest of the Karanas. Remember, the moon blew up and we suffered through the Shattering, so things aren't necessarily familiar. We have Runnyeye, Crushbone, Rivervale, the Feerott, Everfrost, Dealthfist Citadel, all kinds of exciting things. Here's a
Zone List. Oh, we just rediscovered Kunark!
People aren't in the cities because they are our adventuring. Try joining some world-wide channels to hook up with people (right click on your chat window for options).