My binds are usually 1, 2, 3, 4, 5, 6, E, R, T, G, V, X since I use a split keyboard. For marking I took hotbar 6 (since I don't use it), bound the keys to 7 through = and the alt variants (so it's a full bar) and assigned 5 marks, 3 CC, and 2 ignores. I then hid the bar and shared it across classes so that I can mark with any class using those hotkeys.